Obama to take first of two oaths of office Sunday

WASHINGTON: Barack Obama will Sunday be sworn in to shoulder the power and burden of the US presidency for a second term, launching two days of inaugural rituals darkened by domestic discord and crises abroad.

Democrat Obama, 51, will swear to faithfully execute the office of president at a low-key ceremony in the Blue Room of the White House, to comply with the US Constitution, which dictates his first term ends at noon on January 20.

In a tradition honored when that date falls on a Sunday, Obama will repeat the oath in a time-honored public ceremony on Monday, and deliver his inaugural address to Americans, and the watching world, outside at a chilly US Capitol.

Obama's second inauguration, which comes courtesy of an election win over Republican Mitt Romney in November, lacks the hope and history which pulsated through his swearing in as the first black American president in 2009.

Since then, a graying Obama has been battered by a weak economic recovery, failed to meet hugely elevated expectations for his presidency and waged a political war of attrition Republicans, which often slides into the gutter.

He begins anew with several fierce budget battles looming in Congress, and with his "Yes we Can" rhetoric soured by sarcasm over the blocking tactics of Republicans in the partisan brouhaha paralyzing government in Washington.

While polls show Obama's approval ratings above 50 per cent -- far higher than the reviled Congress, they also indicate that many Americans, wearied by a stop-start recovery, doubt their country is headed in the right direction.

Abroad, the US confrontation with Iran is fast headed to a critical point with the specter of military action becoming ever more real, the longer diplomacy over Tehran's nuclear program is stuck in neutral.

Recent terror strikes which killed Americans in Benghazi and Algeria meanwhile call into question Obama's election year soundbite that "Al-Qaeda is on the run" despite the killing of Osama bin Laden in Pakistan.

Increasing muscle flexing by China and rising tensions in contested waters with its neighbors, as well as North Korea's nuclear belligerence, will meanwhile test the president's signature pivot of US diplomacy to Asia.

As he raises his right hand, 224 years after George Washington took the first oath of office to lead a new nation, Obama also knows that for second term presidents, power quickly wanes and political potholes await.

The second term "curse" often strikes: Richard Nixon resigned, Bill Clinton was impeached, George W. Bush's image was shattered by Iraq and Hurricane Katrina and Ronald Reagan's legacy was marred by the Iran-Contra scandal.

Obama has already said that he will root his second term on the crusade to build a more equitable economy which powered his triumph over multi-millionaire Romney.

"I intend to carry out the agenda that I campaigned on, an agenda for new jobs, new opportunity and new security for the middle class," Obama said last week.

After being sworn in surrounded by close family, Obama will put the finishing touches on his inaugural address.

Aides have offered few previews of what he will say on Monday, though such occasions offer the chance for presidents to stress national unity, and to bind wounds of the kind of acrimonious elections like the one Obama won in 2012.

Obama has been seen with yellow legal pads full of ideas for his speech, which will likely be high on poetry but low on policy: his State of the Union Address on February 12 will flesh out his agenda.

But the president will have a message for allies and enemies abroad, and could shape the political ground for top agenda priorities including immigration and energy reform and new gun control laws.

After Monday's solemn ceremony will come celebration, as Obama returns to the White House down a parade route lined with crowds, before a night of glittering inaugural balls -- though the festivities have been trimmed in recognition of the tough times many Americans are still enduring.

On Saturday, Obama and his wife Michelle grabbed paintbrushes for an inaugural day of service at a Washington DC school.

The president, wearing khaki trousers and a button down shirt, and the first lady, in a purple shirt and black leggings, helped stain a bookshelf along with two members of a group that works to keep children in school.

Obama later joked that "Michelle said I did a fine job."

There has been an immense security build-up ahead of the inauguration, with cameras and barricades covering much of the route leading up to the Capitol. Thousands of police will also fan the area on Monday: several at each street corner.

- AFP/ck

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'Glee' accused of ripping off indy YouTube singer

Have they been naughty?

(Credit:
GleeSeason4Songs/YouTube Screenshot by Chris Matyszczyk/CNET)

"That's mine!"

"No, it isn't! It's mine!"

Such is the dialogue I imagine the writers of "Glee" would pen to describe a slight kerfuffle between its own creators and Jonathan Coulton.

Coulton enjoys a bit of fame on YouTube. He writes tunes like "Code Monkey." He created the themes of Portal video games.

He clearly enjoys his art. But he isn't "Glee."

Still, his version of "Baby Got Back," the Sir Mix-A-Lot song, has many admirers. It was less than gleeful for him, then, when he received word that the Fox teeny show appeared to be offering a version that seemed stunningly like his own.

It was to be featured in its January 24 edition.

Coulton tweeted: "Hey look, @GLEEonFOX ripped off my cover of Baby Got Back: http://bit.ly/WME9Ho. Never even contacted me. Classy."

More Technically Incorrect

In case you're unfamiliar with the song, it's all about the wonders of large bottoms.

To my own Saturday ears, Coulton might have a little justification for feeling that the people behind "Glee" are, indeed, large bottoms themselves.

As one of the more than 4,000 people who have retweeted Coulton's plaintive tweet, Greg Pak, offered: "Dude. They even kept the 'Johnny C's in trouble' line," -- a line that was all Coulton's.

Wired thought it might be an idea to contact Fox to ask the organization whether its own ears noticed a marginal resemblance between the two versions.

Sadly, Fox appears to have considered the question very carefully and finally got back with a mere "no comment."

Coulton told Wired:

I'm still waiting on the science. It's possible they chose to reproduce the arrangement exactly, but I'm not sure why they would have kept all my bad choices in there and not found one thing to improve. Though I will say their mix is better than my 2005 version, so that's good.

You will be stunned to hear that Coulton is also waiting on the law. He is musing as to whether he might have recourse against Fox.

He described its apparent purloining of his version as "kind of gross."

The @GleeOnFox Twitter account has stayed silent on the subject, despite being subjected to many inquiring, angry minds.

Its last tweet, sent yesterday, excitedly shrieked: ".@Rach21695 We're ready to be back this Thursday! #glee."

What a comeback.

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Attack at Algeria Gas Plant Heralds New Risks for Energy Development

The siege by Islamic militants at a remote Sahara desert natural gas plant in Algeria this week signaled heightened dangers in the region for international oil companies, at a time when they have been expanding operations in Africa as one of the world's last energy frontiers. (See related story: "Pictures: Four New Offshore Drilling Frontiers.")

As BP, Norway's Statoil, Italy's Eni, and other companies evacuated personnel from Algeria, it was not immediately clear how widely the peril would spread in the wake of the hostage-taking at the sprawling In Amenas gas complex near the Libyan border.

Map by National Geographic

Algeria, the fourth-largest crude oil producer on the continent and a major exporter of natural gas and refined fuels, may not have been viewed as the most hospitable climate for foreign energy companies, but that was due to unfavorable financial terms, bureaucracy, and corruption. The energy facilities themselves appeared to be safe, with multiple layers of security provided both by the companies and by government forces, several experts said. (See related photos: "Oil States: Are They Stable? Why It Matters.")

"It is particularly striking not only because it hasn't happened before, but because it happened in Algeria, one of the stronger states in the region," says Hanan Amin-Salem, a senior manager at the industry consulting firm PFC Energy, who specializes in country risk. She noted that in the long civil war that gripped the country throughout the 1990s, there had never been an attack on Algeria's energy complex. But now, hazard has spread from weak surrounding states, as the assault on In Amenas was carried out in an apparent retaliation for a move by French forces against the Islamists who had taken over Timbuktu and other towns in neighboring Mali. (See related story: "Timbuktu Falls.")

"What you're really seeing is an intensification of the fundamental problem of weak states, and empowerment of heavily armed groups that are really well motivated and want to pursue a set of aims," said Amin-Salem. In PFC Energy's view, she says, risk has increased in Mauritania, Chad, and Niger—indeed, throughout Sahel, the belt that bisects North Africa, separating the Sahara in the north from the tropical forests further south.

On Thursday, the London-based corporate consulting firm Exclusive Analysis, which was recently acquired by the global consultancy IHS, sent an alert to clients warning that oil and gas facilities near the Libyan and Mauritanian borders and in Mauritania's Hodh Ech Chargui province were at "high risk" of attack by jihadis.

"A Hot Place to Drill"

The attack at In Amenas comes at a time of unprecedented growth for the oil industry in Africa. (See related gallery: "Pictures: The Year's Most Overlooked Energy Stories.") Forecasters expect that oil output throughout Africa will double by 2025, says Amy Myers Jaffe, executive director of the energy and sustainability program at the University of California, Davis, who has counted 20 rounds of bidding for new exploration at sites in Africa's six largest oil-producing states.

Oil and natural gas are a large part of the Algerian economy, accounting for 60 percent of government budget revenues, more than a third of GDP and more than 97 percent of its export earnings. But the nation's resources are seen as largely undeveloped, and Algeria has tried to attract new investment. Over the past year, the government has sought to reform the law to boost foreign companies' interests in their investments, although those efforts have foundered.

Technology has been one of the factors driving the opening up of Africa to deeper energy exploration. Offshore and deepwater drilling success in the Gulf of Mexico and Brazil led to prospecting now under way offshore in Ghana, Mozambique, and elsewhere. (See related story: "New Oil—And a Huge Challenge—for Ghana.") Jaffe says the Houston-based company Anadarko Petroleum has sought to transfer its success in "subsalt seismic" exploration technology, surveying reserves hidden beneath the hard salt layer at the bottom of the sea, to the equally challenging seismic exploration beneath the sands of the Sahara in Algeria, where it now has three oil and gas operations.

Africa also is seen as one of the few remaining oil-rich regions of the world where foreign oil companies can obtain production-sharing agreements with governments, contracts that allow them a share of the revenue from the barrels they produce, instead of more limited service contracts for work performed.

"You now have the technology to tap the resources more effectively, and the fiscal terms are going to be more attractive than elsewhere—you put these things together and it's been a hot place to drill," says Jaffe, who doesn't see the energy industry's interest in Africa waning, despite the increased terrorism risk. "What I think will happen in some of these countries is that the companies are going to reveal new securities systems and procedures they have to keep workers safe," she says. "I don't think they will abandon these countries."

This story is part of a special series that explores energy issues. For more, visit The Great Energy Challenge.

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Algeria Hostage Crisis Over, One American Dead

After the Algerian military's final assault on terrorists holding hostages at a gas complex, the four-day hostage crisis is over, but apparently with additional loss of life among the foreign hostages.

One American, Fred Buttaccio of Texas, has been confirmed dead by the U.S. State Department. Two more U.S. hostages remain unaccounted for, with growing concern among U.S. officials that they did not survive.

But another American, Mark Cobb of Corpus Christi, Texas is now confirmed as safe. Sources close to his family say Cobb, who is a senior manager of the facility, is safe and reportedly sent a text message " I'm alive."

Inside Algerian Hostage Crisis, One American Dead Watch Video

American Hostages Escape From Algeria Terrorists Watch Video

In a statement, President Obama said, "Today, the thoughts and prayers of the American people are with the families of all those who were killed and injured in the terrorist attack in Algeria. The blame for this tragedy rests with the terrorists who carried it out, and the United States condemns their actions in the strongest possible terms. ... This attack is another reminder of the threat posed by al Qaeda and other violent extremist groups in North Africa."

According to Algerian state media, 32 militants are dead and a total of 23 hostages perished during the four-day siege of the In Amenas facility in the Sahara. The Algerian Interior Ministry also says 107 foreign nationals who worked at the facility for BP and other firms were rescued or escaped from the al Qaeda-linked terrorists who took over the BP joint venture facility on Wednesday.

The Japanese government says it fears "very grave" news, with multiple casualties among the 10 Japanese citizens working at the In Amenas gas plant.

Five British nationals and one U.K. resident are either deceased or unaccounted for in the country, according to British Foreign Minister William Hague. Hague also said that the Algerians have reported that they are still trying to clear boobytraps from the site.

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NASA planet-hunter is injured and resting

Lisa Grossman, physical sciences reporter

(Image: NASA/Kepler mission/Wendy Stenzel)

NASA's planet-hunting Kepler telescope has put its search for alien Earths on hold while it rests a stressed reaction wheel.

The injured wheel normally helps to control the telescope's orientation, keeping it pointed continuously at the same patch of sky. Kepler stares at the thousands of stars in its field of view to watch for the telltale blinks that occur when a planet crosses in front of its star. It has found nearly 3000 potential planets outside our solar system since its launch in 2009, transforming the field of exoplanet research and raising hopes of someday finding alien life.

When it launched, Kepler had four reaction wheels: three to control its motion along each axis, and one spare. But last July, one wheel stopped turning. If the spacecraft loses a second wheel, the mission is over.

So when another wheel started showing signs of elevated friction on 7 January, the team decided to play it safe. After rotating the spacecraft failed to fix the problem, NASA announced yesterday that they're placing Kepler in safe mode for 10 days to give the wheel a chance to recover.

The hope is that the lubricating oil that helps the wheel's ball bearings run smoothly around a track will redistribute itself during the rest period.

The telescope can't take any science data while in safe mode. But if the wheel recovers on its own, Kepler's extended mission will run until 2016, leaving it plenty of time to make up for the lost days.

"Kepler is a statistical mission," says Charlie Sobeck, Kepler's deputy project manager at NASA's Ames Research Centre in Mountain View, California. "In the long run, as long as we make the observations, it doesn't matter a lot when we make the observations."

Despite the high stakes, the team doesn't seem too worried.

"Each wheel has its own personality, and this particular wheel has been something of a free spirit," Sobeck says. "It's had elevated torques throughout the mission. This one is typical to what we've seen in the past, and if we had four good wheels we probably wouldn't have taken any action."

"I prefer to picture the spacecraft lounging at the shore of the cosmic ocean sipping a Mai Tai so that she'll be refreshed and rejuvenated for more discoveries," wrote Kepler co-investigator Natalie Batalha in an email.

The team will check up on the wheel on 27 January and return to doing science as soon as possible.

There are two exoplanet missions currently being considered for after Kepler is finished, says Doug Hudgins at NASA Headquarters in Washington, DC. One, TESS (Terrestrial Exoplanet Survey Satellite), would scan the entire sky for planets transiting the stars nearest to the sun. The other, FINESSE (Fast Infrared Exoplanet Spectroscopy Survey Explorer), would take spectra of planets as they passed in front of their stars as a way to probe their atmospheres.

The missions are being evaluated now, and NASA will probably select one this spring, Hudgins says. The winner will launch in 2017.

If Kepler goes down with its reaction wheel, that won't affect which mission wins, he adds. "That's a straight-up competition based on the merits of the two concept study reports."

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Cycling: 'I want to compete again,' Armstrong says

 

LOS ANGELES: Disgraced US cyclist Lance Armstrong said in an interview aired Friday that he wants to take part in competitive sports again, even after being banned for doping and stripped of his honors.

"Hell, yes. I'm a competitor. It's what I've done my whole life. I love to train. I love to race," Armstrong told Oprah Winfrey. "Not the Tour de France, but there's a lot of other things I could do. I deserve to be punished. I'm not sure that I deserve a death penalty."

- AFP

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Researcher: Apps meant to spot skin cancer are inaccurate

Researchers ran 188 images of skin lesions through four apps and found that three apps incorrectly described at least 30 percent of the melanomas as benign.

(Credit:
Screenshot by Elizabeth Armstrong Moore/CNET)

When a patient asked Laura Ferris, an assistant professor of dermatology at the University of Pittsburgh School of Medicine, her opinion on smartphone apps that purport to distinguish between benign and malignant skin lesions, Ferris realized she'd never used one and decided to run images of melanomas through a few of the apps herself.

"When I saw the first few results come back of them being missed, I really started to get concerned," Ferris says in a school video. So she decided to investigate further, and reports this week in JAMA Dermatology that three out of four smartphone apps her team tested incorrectly described at least 30 percent of melanomas as "unconcerning."

The news comes the same week a Pew Research Center study found that 35 percent of Americans seek out medical diagnoses (not just remedies or information) online.

For the melanoma study, researchers uploaded 188 images of skin lesions to each of the four applications (they decided "not to make a direct statement about a particular app" and are thus not naming the apps they studied). The apps analyzed the images in different ways, including automated algorithms and images reviewed by an anonymous board-certified dermatologist.

It turns out that of the four melanoma apps studied, the most accurate one was not only the most expensive (costing $5 per image) but also was the only one to rely on the dermatologist to review the images. (In this case, just one of the 53 melanomas uploaded was incorrectly identified as benign.)

These results could be particularly problematic for those without the resources to go to an actual dermatologist or afford the most expensive app, especially if they take an "unconcerning" result as confirmation that they need not spend any more money investigating the area in question.

"If [users] see a concerning lesion but the smartphone app incorrectly judges it to be benign, they may not follow up with a physician," says Ferris, whose study was funded in part by the National Institutes of Health. "Technologies that decrease the mortality rate by improving self- and early-detection of melanomas would be a welcome addition to dermatology, but we have to make sure patients aren't being harmed by tools that deliver inaccurate results."

The researchers further warn that even though the free or low-cost apps are specified as educational only, they are not subject to regulatory oversight and should be used with caution.

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Attack at Algeria Gas Plant Heralds New Risks for Energy Development

The siege by Islamic militants at a remote Sahara desert natural gas plant in Algeria this week signaled heightened dangers in the region for international oil companies, at a time when they have been expanding operations in Africa as one of the world's last energy frontiers. (See related story: "Pictures: Four New Offshore Drilling Frontiers.")

As BP, Norway's Statoil, Italy's Eni, and other companies evacuated personnel from Algeria, it was not immediately clear how widely the peril would spread in the wake of the hostage-taking at the sprawling In Amenas gas complex near the Libyan border.

Map by National Geographic

Algeria, the fourth-largest crude oil producer on the continent and a major exporter of natural gas and refined fuels, may not have been viewed as the most hospitable climate for foreign energy companies, but that was due to unfavorable financial terms, bureaucracy, and corruption. The energy facilities themselves appeared to be safe, with multiple layers of security provided both by the companies and by government forces, several experts said. (See related photos: "Oil States: Are They Stable? Why It Matters.")

"It is particularly striking not only because it hasn't happened before, but because it happened in Algeria, one of the stronger states in the region," says Hanan Amin-Salem, a senior manager at the industry consulting firm PFC Energy, who specializes in country risk. She noted that in the long civil war that gripped the country throughout the 1990s, there had never been an attack on Algeria's energy complex. But now, hazard has spread from weak surrounding states, as the assault on In Amenas was carried out in an apparent retaliation for a move by French forces against the Islamists who had taken over Timbuktu and other towns in neighboring Mali. (See related story: "Timbuktu Falls.")

"What you're really seeing is an intensification of the fundamental problem of weak states, and empowerment of heavily armed groups that are really well motivated and want to pursue a set of aims," said Amin-Salem. In PFC Energy's view, she says, risk has increased in Mauritania, Chad, and Niger—indeed, throughout Sahel, the belt that bisects North Africa, separating the Sahara in the north from the tropical forests further south.

On Thursday, the London-based corporate consulting firm Exclusive Analysis, which was recently acquired by the global consultancy IHS, sent an alert to clients warning that oil and gas facilities near the Libyan and Mauritanian borders and in Mauritania's Hodh Ech Chargui province were at "high risk" of attack by jihadis.

"A Hot Place to Drill"

The attack at In Amenas comes at a time of unprecedented growth for the oil industry in Africa. (See related gallery: "Pictures: The Year's Most Overlooked Energy Stories.") Forecasters expect that oil output throughout Africa will double by 2025, says Amy Myers Jaffe, executive director of the energy and sustainability program at the University of California, Davis, who has counted 20 rounds of bidding for new exploration at sites in Africa's six largest oil-producing states.

Oil and natural gas are a large part of the Algerian economy, accounting for 60 percent of government budget revenues, more than a third of GDP and more than 97 percent of its export earnings. But the nation's resources are seen as largely undeveloped, and Algeria has tried to attract new investment. Over the past year, the government has sought to reform the law to boost foreign companies' interests in their investments, although those efforts have foundered.

Technology has been one of the factors driving the opening up of Africa to deeper energy exploration. Offshore and deepwater drilling success in the Gulf of Mexico and Brazil led to prospecting now under way offshore in Ghana, Mozambique, and elsewhere. (See related story: "New Oil—And a Huge Challenge—for Ghana.") Jaffe says the Houston-based company Anadarko Petroleum has sought to transfer its success in "subsalt seismic" exploration technology, surveying reserves hidden beneath the hard salt layer at the bottom of the sea, to the equally challenging seismic exploration beneath the sands of the Sahara in Algeria, where it now has three oil and gas operations.

Africa also is seen as one of the few remaining oil-rich regions of the world where foreign oil companies can obtain production-sharing agreements with governments, contracts that allow them a share of the revenue from the barrels they produce, instead of more limited service contracts for work performed.

"You now have the technology to tap the resources more effectively, and the fiscal terms are going to be more attractive than elsewhere—you put these things together and it's been a hot place to drill," says Jaffe, who doesn't see the energy industry's interest in Africa waning, despite the increased terrorism risk. "What I think will happen in some of these countries is that the companies are going to reveal new securities systems and procedures they have to keep workers safe," she says. "I don't think they will abandon these countries."

This story is part of a special series that explores energy issues. For more, visit The Great Energy Challenge.

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Armstrong's Lowest Point Was Quitting Livestrong

Lance Armstrong, 41, said tonight that the lowest point in his fall from grace and the top of the cycling world came when his cancer charity, Livestrong, asked him to consider stepping down.

After the U.S. Anti-Doping Agency released a report in October 2012 alleging Armstrong doped throughout his reign as Tour de France champion, Armstrong said a second installment of an interview with Oprah Winfrey, his major sponsors -- including Nike, Anheuser Busch and Trek -- called one by one to end their endorsement contracts with him.

"Everybody out," he said. "Still not the most humbling moment."

Then came the call from Livestrong, the charity he founded at age 25 when he was diagnosed with testicular cancer.

"The story was getting out of control, which was my worst nightmare," he said. "I had this place in my mind that they would all leave. The one I didn't think would leave was the foundation.

"That was most humbling moment," he said.

Armstrong first stepped down as chairman of the board for the charity before being asked to end his association with the charity entirely. Livestrong is now run independently of Armstrong.

"I don't think it was 'We need you to step down,' but, 'We need you to consider stepping down for yourself,'" he said, recounting the call. "I had to think about that a lot. None of my kids, none of my friends have said, 'You're out,' and the foundation was like my sixth child. To make that decision, to step aside, that was big."

George Burns/Harpo Studios, Inc.

Lance Armstrong-Winfrey Interview: How Honest Was He? Watch Video

Lance Armstrong-Winfrey Interview: Doping Confession Watch Video

In the first part of the interview, broadcast Thursday, Armstrong admitted for the first time that his decade-long dominance of cycling and seven wins in the Tour de France were owed, in part, to performance-enhancing drugs and oxygen-boosting blood transfusions.

He told Winfrey that he was taking the opportunity to confess to everything he had done wrong, including for years angrily denying claims that he had doped.

READ MORE: Armstrong Admits to Doping

WATCH: Armstrong's Many Denials Caught on Tape

READ MORE: 10 Scandalous Public Confessions

Armstrong said in the interview that he stopped doping following his 2005 Tour de France victory and did not use banned substances when he placed third in 2009 and entered the tour again in 2010.

Investigators familiar with Armstrong's case, however, told ABC News today that Armstrong did not come completely clean to Winfrey, and that they believed he doped in 2009.

They said that Armstrong's blood values at the 2009 race showed clear blood manipulation consistent with two transfusions. Armstrong's red blood cell count suddenly went up at these points, even though the number of baby red blood cells did not.

Investigators said that was proof that he received a transfusion of mature red blood cells.

READ MORE: Lance Armstrong May Have Lied to Winfrey: Investigators

If Armstrong lied about the 2009 race, it could be to protect himself criminally, investigators said.

Federal authorities looking to prosecute criminal cases will look back at the "last overt act" in which the crime was committed, they explained. If Armstrong doped in 2005 but not 2009, the statute of limitations may have expired on potential criminal activity.

The sources noted that there is no evidence right now that a criminal investigation will be reopened. Armstrong is facing at least three civil suits.

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Matching names to genes: the end of genetic privacy?

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Are we being too free with our genetic information? What if you started receiving targeted ads for Prozac for the depression risk revealed by your publicly accessible genome? As increasing amounts of genetic information is placed online, many researchers believe that guaranteeing donors' privacy has become an impossible task.

The first major genetic data collection began in 2002 with the International HapMap Project – a collaborative effort to sequence genomes from families around the world. Its aim was to develop a public resource that will help researchers find genes associated with human disease and drug response.

While its consent form assured participants that their data would remain confidential, it had the foresight to mention that with future scientific advances, a deliberate attempt to match a genome with its donor might succeed. "The risk was felt to be very remote," says Laura Lyman Rodriguez of the US government's National Human Genome Research Institute in Bethesda, Maryland.

Their fears proved to be founded: in a paper published in Science this week, a team led by Yaniv Erlich of the Whitehead Institute in Cambridge, Massachusetts, used publicly available genetic information and an algorithm they developed to identify some of the people who donated their DNA to HapMap's successor, the 1000 Genomes Project.

Anonymity not guaranteed

Erlich says the research was inspired by a New Scientist article in which a 15-year-old boy successfully used unique genetic markers called short tandem repeats (STRs) on his Y chromosome to track down his father, who was an anonymous sperm donor. Erlich and his team used a similar approach.

First they turned to open-access genealogy databases, which attempt to link male relatives using matching surnames and similar STRs. The team chose a few surnames from these sources, such as "Venter",and then searched for the associated STRs in the 1000 Genomes Project's collection of whole genomes. This allowed them to identify which complete genomes were likely to be from people named Venter.

Although the 1000 Genome Project's database, which at last count had 1092 genomes, does not contain surname data, it does contain demographic data such as the ages and locations of its donors. By searching online phonebooks for people named Venter and narrowing those down to the geographic regions and ages represented in the whole genomes, the researchers were able to find the specific person who had donated his data.

In total, the researchers identified 50 individuals who had donated whole genomes. Some of these were female, whose identity was given away because of having the same location and age as a known donor's wife.

Matter of time

Before publishing their findings, the team warned the US National Institutes of Health (NIH) and other institutions involved in the project about the vulnerability in their data. Rodriguez says that they had been anticipating that someone would identify donors, "although we didn't know how or when".

To prevent Erlich's method from being used successfully again, age data has been removed from the project's website. Erlich says that this makes it difficult, although not impossible, to narrow the surnames down to an individual.

"The genie's out of the bottle," says Jeffrey Kahn of Florida State University in Tallahassee. "It's a harbinger of a changing paradigm of privacy." A cultural zeitgeist led by companies such as Facebook has led to more information sharing than anyone would have thought possible back in 2002 when HapMap first began, he says.

Recurring problem

This is not the first time genome confidentiality has been compromised. When James Watson made his genome public in 2007, he blanked out a gene related to Alzheimer's. But a group of researchers successfully inferred whether he carried the risky version of this gene by examining the DNA sequences on either side of the redacted gene.

While someone is bound to find another way to identify genetic donors, says Rodriguez, the NIH believes it would be wrong to remove all of their genome data from the public domain. She says that full accessibility is "very beneficial to science", but acknowledges that the project needs to strike a careful balance between confidentiality and open access.

It is especially pertinent, says Kahn, because genetic data does not just carry information from the person from whom it was taken. It can also reveal the genetic details of family members, some of whom might not want that information to be public. A relative's genome might reveal your own disease risk, for example, which you might not want to know or have an employer learn of. While laws prohibit health insurers and employers from discriminating against people based on their genetic data, it would not be difficult to give another reason for denying you a job.

An individual's relatives could not prevent that individual from learning about themselves, says Rodriguez, but researchers should encourage would-be genome donors to discuss the risks and benefits with their families.

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